Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients

NANot yet recruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

August 25, 2025

Primary Completion Date

May 19, 2029

Study Completion Date

May 19, 2029

Conditions
OSA - Obstructive Sleep Apnea
Interventions
DEVICE

Endoscopic Sleeve Gastropathy

"Weight loss through diet, exercise, and behavioural changes positively impacts sleep quality. Reduction in body weight can alleviate OSA symptoms and improve overall sleep architecture1,2,3 Surgical weight loss procedures play a crucial role in managing obesity-related health issues, including OSA.4 Endobariatric procedures, including Endoscopic Sleeve Gastroplasty (ESG), have gained attention as a weight loss solution with the potential for improving obesity-related health issues.~ESG involves suturing the stomach to reduce its size, limiting food intake. Unlike traditional bariatric surgeries, ESG doesn't require incisions. ESG has shown promise in achieving clinically significant weight loss, up to 20% of TBWL. By reducing stomach capacity, it promotes satiety and calorie restriction. ESG is generally safe, with fewer complications compared to more invasive procedures"

OTHER

Lifestyle Modification alone

Participants will follow a structured program involving a low-calorie diet (typically 1200-1500 kcal/day), regular physical activity (150 minutes of moderate-intensity exercise per week), and behavioural therapy sessions.

All Listed Sponsors
lead

Asian Institute of Gastroenterology, India

OTHER

NCT07082608 - Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients | Biotech Hunter | Biotech Hunter