A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

340

Participants

Timeline

Start Date

July 29, 2025

Primary Completion Date

April 23, 2026

Study Completion Date

July 17, 2026

Conditions
Obesity or Overweight
Interventions
DRUG

RO7795081

RO7795081 will be administered orally once daily, according to the randomized dosing regimen, during the 38-week treatment period.

DRUG

Placebo

Placebo matching each RO7795081 dosing regimen arm will be administered orally once daily during the 38-week treatment period.

Trial Locations (37)

11516

Neurobehavioral Research, Inc., Cedarhurst

19114

Tristar Clinical Investigations, Philadelphia

20009

Emerson Clinical Research Institute LLC, Washington D.C.

20110

Manassas Clinical Research Center, Manassas

27103

Accellacare Research of Winston Salem, Winston-Salem

27518

Accellacare of Cary - Cary Medical Group, Cary

Accellacare of Cary, Cary

27609

Accellacare of Raleigh, Raleigh

27804

Accellacare of Rocky Mount, Rocky Mount

28144

Accellacare of Salisbury, Salisbury

28401

Accellacare of Wilmington, LLC, Wilmington

28601

Accellacare - Hickory, Hickory

28625

Accellacare of Piedmont Healthcare, Statesville

30291

Rophe Adult and Pediatric Medicine/SKYCRNG, Union City

32159

K2 Medical Research - The Villages, Lady Lake

32751

K2 Medical Research-Maitland, Maitland

32806

K2 Medical Research South Orlando, LLC, Orlando

36207

Pinnacle Research Group, Anniston

37203

Clinical Research Associates, Nashville

37620

Internal Medicine and Pediatrics Associates of Bristol, Bristol

37909

Alliance for Multispecialty Research. LLC, Knoxville

37912

Accellacare of Knoxville, Knoxville

37938

Knoxville-Summit-Halls Family Practice, Knoxville

50010

McFarland Clinic under Accellacare, Ames

59701

Mercury Street Medical Group, PLLC, Butte

73069

Alliance for Multispecialty Research, LLC (AMR Norman), Norman

75230

Velocity Clinical Research, Dallas

77040

Juno Research, LLC, Houston

77401

Apex Mobile Clinical Research, Bellaire

78231

Consano Clinical Research, Shavano Park

78731

Texas Diabetes & Endocrinology, P.A., Austin

84790

Chrysalis Clinical Research, St. George

91403

Asclepes Research Centers, Sherman Oaks

91730

Prospective Research Innovations Inc., Rancho Cucamonga

91978

Encompass Clinical Research, Spring Valley

92630

Orange County Research Center, Lake Forest

06708-3346

Chase Medical Research, Waterbury

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY