Effects of Manual Positive End Expiratory Pressure and Non-invasive Continuous Positive Air Pressure in COPD Patients

NANot yet recruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

July 28, 2025

Primary Completion Date

November 28, 2025

Study Completion Date

December 10, 2025

Conditions
COPD
Interventions
DEVICE

Manual Positive End Expiratory Pressure (PEEP) Therapy

Participants in this group receive Manual Positive End Expiratory Pressure (PEEP) therapy. The intervention is delivered using a tight-fitting mask that applies positive pressure at the end of expiration, helping to keep the alveoli open, enhance oxygenation, and prevent airway collapse. The therapy is administered according to a structured protocol over a 4-week period, aiming to reduce breathlessness, improve lung function, and support ventilation. Along with PEEP, participants also receive baseline Active Cycle of Breathing Techniques (ACBTs) for airway clearance and breathing control.

DEVICE

Non-Invasive CPAP Therapy

Participants in this group receive Non-Invasive Continuous Positive Airway Pressure (CPAP) therapy. CPAP provides a constant level of positive pressure throughout the entire breathing cycle using a non-invasive ventilator and a full-face or nasal mask. This therapy improves gas exchange, reduces the work of breathing, and eases symptoms such as dyspnea. Like Group A, CPAP therapy is delivered following a standardized protocol for 4 weeks, and participants also perform baseline ACBTs to support respiratory function.

Trial Locations (1)

40100

Arjumand, Lahore

All Listed Sponsors
lead

Riphah International University

OTHER