Comparing Vascular Responses to Aerobic Exercise With and Without Blood Flow Restriction in Young and Older Adults

NANot yet recruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

October 6, 2025

Primary Completion Date

May 29, 2026

Study Completion Date

July 31, 2026

Conditions
AgeingBlood Flow Restriction (BFR) Training Effects
Interventions
OTHER

Low Intensity Aerobic Exercise with Blood Flow Restriction (LIAE+BFR)

"In the LIAE+BFR condition, participants will walk on a treadmill for 20 minutes at 30-40% of heart rate reserve (HRR), with a pneumatic cuff inflated to 1.3 times the individual's ankle systolic blood pressure, using a 5cm wide x 75cm long commercial cuff around each upper thigh.~Treadmill speed will be adjusted dynamically to maintain target intensities, while the incline remains at 1%. Heart Rate, the Modified Borg Rate of Perceived Exertion scale, and the Rating of perceived discomfort will be continuously monitored throughout both exercise sessions to ensure adherence to the prescribed intensity levels."

OTHER

High Intensity Interval Exercise (HIIE)

"In the HIIE condition, participants will perform a 20 minutes treadmill-based HIAE, alternating between 60-seconds high-intensity intervals at 60-89% HRR and 60-second active recovery intervals at 40-50% HRR.~Treadmill speed will be adjusted dynamically to maintain target intensities, while the incline remains at 1%. Heart Rate, the Modified Borg Rate of Perceived Exertion scale, and the Rating of perceived discomfort will be continuously monitored throughout both exercise sessions to ensure adherence to the prescribed intensity levels."

Trial Locations (1)

2829-511

Egas Moniz School of Health and Science, Almada

All Listed Sponsors
lead

Egas Moniz - Cooperativa de Ensino Superior, CRL

OTHER