NCT07078721View on ClinicalTrials.gov

Efficacy and Safety of UCBT With TMI -Based Conditioning Regimen for Adults With Refractory/Relapsed Aplastic Anemia

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

July 20, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

June 30, 2028

Conditions
Aplastic Anemia Idiopathic
Interventions
RADIATION

Total Marrow Irradiation

\- TMI 4 Gy qd on Day -2;

DRUG

Fludarabine (FLU)

Flu 30 mg/m² × 5 days on Days -6, -5, -4, -3, -2;

DRUG

Melphalan (Mel)

Mel 100 mg/m² qd on Day -1.

Trial Locations (1)

300020

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin

All Listed Sponsors
lead

Institute of Hematology & Blood Diseases Hospital, China

OTHER