NCT07076472View on ClinicalTrials.gov

Sonodynamic Therapy With SONALA-001 and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma

PHASE1RecruitingINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

August 14, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Progressive GlioblastomaRecurrent Glioblastoma
Interventions
DRUG

Aminolevulinic Acid Intravenous Formulation SONALA-001

Given IV

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Computed Tomography

Undergo CT

OTHER

Electronic Health Record Review

Ancillary studies

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

MRI-Guided Focused Ultrasound Ablation

Undergo transcranial MRgFUS

Trial Locations (1)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

Mayo Clinic
All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Mayo Clinic

OTHER

NCT07076472 - Sonodynamic Therapy With SONALA-001 and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma | Biotech Hunter | Biotech Hunter