Neuroimaging and Biomarkers of Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy

RecruitingOBSERVATIONAL
Enrollment

36

Participants

Timeline

Start Date

September 19, 2025

Primary Completion Date

September 30, 2027

Study Completion Date

December 31, 2027

Conditions
CAR T-Cell Therapy
Interventions
OTHER

Brain magnetic resonance imaging, neurocognitive assessments, quality of life questionnaire, biomarkers

Pathognomonic magnetic resonance imaging; neurocognitive assessments with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS); quality of life assessment with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire 30; measurement of liquid biomarkers.

Trial Locations (1)

92093

RECRUITING

University of California, San Diego, La Jolla

All Listed Sponsors
lead

University of California, San Diego

OTHER

NCT07075523 - Neuroimaging and Biomarkers of Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy | Biotech Hunter | Biotech Hunter