Clinical Study Evaluating the Efficacy and Safety of Colchicine in Adult Patients With Sepsis

fluid resuscitation a minimum of 30 mL/kg of intravenous (IV) crystalloid fluid administered during the initial 3 hours of resuscitation, along with empiric antibiotic therapy aimed at the suspected pathogens and infection sites, ideally starting within the first hour.

colchicine 500 mcg oral twice daily plus conventional sepsis therapy for 5 days.