47
Participants
Start Date
November 1, 2024
Primary Completion Date
August 1, 2028
Study Completion Date
November 1, 2028
Induction therapy-3 cycles of BvC (Brentuximab vedotin plus Chidamide)
"3 cycles of BvC treatment for all enrolled patients.~Brentuximab vedotin; Specification: 50mg per vial; 1.8mg/kg qd d1 every 3 weeks, ivgtt.;~Chidamide; Specification: 5mg per tablet; 20mg biw for 2 weeks every 3 weeks, po.;"
Consolidation therapy- 3 or 6 cycles of BvC(Brentuximab vedotin plus chidamide)
"Consolidation therapy( For patients who achieved CR after induction therapy, 3 cycles of additional BvC treatment; For patients who achieved PR after induction therapy, 6 cycles of additional BvC treatment).~Brentuximab vedotin; Specification: 50mg per vial; 1.8mg/kg qd d1 every 3 weeks, ivgtt.;~Chidamide; Specification: 5mg per tablet; 20mg biw for 2 weeks every 3 weeks, po.;~Maintenance therapy chidamide (20mg biw for 2 weeks every 3 weeks, po.) for ≥2 years"
Maintenance therapy-chidamide
Chidamide (20mg biw for 2 weeks every 3 weeks, po.) for ≥2 years
RECRUITING
The First Affiliated Hospital of Soochow University, Suzhou
The First Affiliated Hospital of Soochow University
OTHER