90
Participants
Start Date
January 3, 2023
Primary Completion Date
January 31, 2024
Study Completion Date
January 31, 2024
Metformin Monotherapy
Participants in this group (n = 30) received metformin alone, administered in a daily dose of 1000 to 2000 mg divided into two doses, over a period of four weeks.
Metformin combined with probiotic (Normia® Jadran Galenski Laboratory) supplementation
Participants (n = 30) received metformin (1000-2000 mg/day, divided in two doses) combined with a probiotic supplement (1 capsule three times daily) over a four-week period.
Triple therapy - metformin, probiotic and ursodeoxycholic acid (Bilexin®, Bosnalijek)
Participants in this group (n = 30) were treated with a combination of metformin (1000 - 2000 mg/day), a probiotic (1 capsule three times daily) and ursodeoxycholic acid (UDCA, 1 capsule (250mg) three times daily) for four weeks.
Public Health Institution Dom zdravlja Banja Luka, Banja Luka
University of Banja Luka
OTHER