Regorafenib (Reg) and Lorigerlimab (Lor), RELO Regimen, in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy [ReLOAD Trial]

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

May 1, 2027

Study Completion Date

May 1, 2029

Conditions
Colorectal CancerRegorafenibHigh Risk Patients
Interventions
DRUG

Regorafenib (CT)

Given by po

DRUG

Lorigerlimab

Given by IV

Trial Locations (1)

77030

MD Anderson Cancer Center, Houston

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Bayer

INDUSTRY

collaborator

MacroGenics

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER