NCT07070232 - A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors | Biotech Hunter

Enrollment

550

Participants

Timeline

Start Date

August 12, 2025

Primary Completion Date

May 31, 2028

Study Completion Date

February 28, 2030

Conditions

Advanced Solid Tumor

Interventions

DRUG

BNT326

Intravenous (IV) infusion

DRUG

BNT327

IV infusion

DRUG

Itraconazole

Oral administration

DRUG

Paroxetine

Oral administration

Trial Locations (9)

34232

RECRUITING

Florida Cancer Specialists, Sarasota

49546

RECRUITING

START Midwest, LLC, Grand Rapids

78229

RECRUITING

South Texas Accelerated Research Therapeutics (START), LLC, San Antonio

84119

RECRUITING

START Mountain Region, West Valley City

NW3 2QG

RECRUITING

Royal Free Hospital, London

SW3 6JJ

RECRUITING

Royal Marsden Hospital-London, London

W12 0HS

RECRUITING

Imperial College London, London

M20 4BX

RECRUITING

The Christie Hospital, Manchester

SM2 5PT

RECRUITING

Royal Marsden Hospital, Sutton