Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine Without Aura

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

June 1, 2027

Conditions
Migraine Without Aura
Interventions
DEVICE

Fu's Subcutaneous Needling

Participants were seated while the practitioner identified affected muscles (sternocleidomastoid, scalene, splenius capitis, and upper trapezius) via sliding palpation. After routine disinfection, a disposable FSN needle (Nanjing Paifu Medical Technology Co., Ltd., Jiangsu, China) was inserted parallel to the subcutaneous loose connective tissue surrounding the affected muscle. Once fully inserted, the soft tube stand was secured in the slot. After confirming no pain, the practitioner performed smooth, gentle, fan-shaped swaying movements (120° angle, \~100 times/min) with the index and ring fingers. This was accompanied by reperfusion activities-resistance-based contraction and relaxation of the affected muscles, performed collaboratively by the practitioner and participant. Each set comprised 20 swaying movements and 10 seconds of reperfusion, repeated three times per muscle.

DRUG

Flunarizine Hydrochloride

Participants in the drug group were administered 5 mg flunarizine hydrochloride capsules nightly before sleep for 4 weeks.

All Listed Sponsors
lead

Guangzhou University of Chinese Medicine

OTHER