Weaning Approaches for Vasopressin in Sepsis

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

October 1, 2028

Conditions
Septic Shock
Interventions
OTHER

Titrated weaning of vasopressin.

The titrated group will follow the vasopressin weaning protocol used in the DOVSS study (reduction of 0.01 U/min per hour).

OTHER

Abrupt weaning of vasopressin.

The abrupt group will discontinue the vasopressin infusion at the time of randomization, without dose titration.

All Listed Sponsors
lead

Hospital Nossa Senhora da Conceicao

OTHER