The Mepilex Cesarean Delivery Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Surgical Site Infection Following Cesarean Delivery
Interventions
DEVICE

Mepilex Ag Dressing

A silver-impregnated antimicrobial foam dressing (Mepilex Ag) will be placed over the cesarean incision immediately following skin closure in the operating room. Participants assigned to this intervention will be instructed to leave the dressing in place for 7 days, in accordance with manufacturer guidelines, unless earlier removal is necessary due to dressing saturation, displacement, or clinical concern. Mepilex Ag is FDA-cleared for use as a wound dressing and is designed to maintain a moist wound environment while providing sustained antimicrobial protection to help reduce the risk of surgical site infection.

DEVICE

Standard Surgical Dressing (Telfa non-adhesive dressing, gauze, and Primapore adhesive bandage)

A standard postoperative dressing consisting of a sterile Telfa non-adhesive pad placed over the cesarean incision, covered with gauze, and secured with a Primapore adhesive bandage. The dressing is applied immediately following skin closure in the operating room as part of routine institutional care. It is typically removed within 24 to 48 hours postoperatively, depending on wound condition and provider discretion.

Trial Locations (1)

10461

Jack D. Weiler Hospital (Einstein Campus), The Bronx

All Listed Sponsors
lead

Montefiore Medical Center

OTHER

NCT07066254 - The Mepilex Cesarean Delivery Trial | Biotech Hunter | Biotech Hunter