Serplulimab Combined With Cryoablation for Early-Stage Non-Small Cell Lung Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

September 30, 2027

Conditions
Early Lung Cancer
Interventions
DRUG

Serplulimab

PD-1 inhibitor, 300 mg intravenous infusion, once every 3 weeks (Q3W) for up to 6 cycles, starting after cryoablation recovery and in the absence of major procedural complications.

PROCEDURE

CT-guided Cryoablation

Percutaneous cryoablation performed under CT guidance to achieve local tumor ablation. Procedure done once (per-protocol) prior to systemic therapy.

Trial Locations (1)

200032

Zhongshan Hospital Affiliated to Fudan University, No. 180 Fenglin Road, Xuhui District,, Shanghai

All Listed Sponsors
lead

Xi Junjie

OTHER