66
Participants
Start Date
May 16, 2025
Primary Completion Date
May 15, 2028
Study Completion Date
May 15, 2028
Adjuvant Concurrent Chemoradiotherapy with Simultaneous Integrated Boost
Eligibility patients will receive IMRT or VMAT. The prescription dose to high-risk area of tumor bed or positive lymph node was planned at 55-60Gy and the prescription dose to lymphatic drainage regions was planned at 40-45Gy in 20-25 fractions. During radiotherapy, patients will concurrently receive capecitabine (1600 mg/m² on days 1-14, every 21 days for 2 cycles). After radiotherapy, maintenance therapy with capecitabine will continue (2000 mg/m² on days 1-14, every 21 days for 6 cycles). For patients who cannot tolerate capecitabine, S-1 will be used as an alternative.
RECRUITING
Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
OTHER