ABY-029 Glioma Trial

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

July 31, 2028

Study Completion Date

December 31, 2028

Conditions
Intracranial Tumor
Interventions
DRUG

ABY-029

"ABY-029 will be administered via single intravenous injection to subjects with high-grade glioma approximately 1-3 hours prior to surgery.~All research procedures will occur during surgery. The research procedures involve image and measurement data collection and biopsy specimen sampling. Research data collection will occur at 3 or 4 time points during surgery using either standard-of-care tools and methods or non-significant risk experimental devices.~No follow-up visit will be required of participants. Participants will be monitored for possible adverse events for approximately 30 days by the operating surgeon involved in the clinical trial procedures and through review of participant medical records."

All Listed Sponsors
collaborator

Dartmouth College

OTHER

collaborator

National Cancer Institute (NCI)

NIH

lead

Dartmouth-Hitchcock Medical Center

OTHER