Acute Effects of Powdered Beetroot Extract Supplementation on the Microcirculation of Resistant Hypertensive Individuals

EARLY_PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Resistant Arterial Hypertension
Interventions
DIAGNOSTIC_TEST

evaluation of systemic microvascular reactivity

Evaluation of systemic microvascular reactivity using laser speckle contrast imaging.

DIAGNOSTIC_TEST

ABPM

Ambulatory blood pressure measuring: systolic, diastolic and mean arterial pressures

DIETARY_SUPPLEMENT

beetroot supplement

A powdered beetroot extract supplement containing 400 mg of nitrate per dose will be used in the supplement group, administered orally at a daily amount of 10 g.

Trial Locations (1)

20397-230

National Institute of Cardiology, Rio de Janeiro

All Listed Sponsors
lead

National Institute of Cardiology, Laranjeiras, Brazil

OTHER_GOV