A Phase III Clinical Study to Compare the Safety and Efficacy of 177Lu-DOTATATE Injection and Long-acting Oxytrexine in Adult Patients With NETs

PHASE3RecruitingINTERVENTIONAL
Enrollment

184

Participants

Timeline

Start Date

December 12, 2023

Primary Completion Date

November 24, 2026

Study Completion Date

February 24, 2027

Conditions
NETS Ga68 Lu177
Interventions
DRUG

177Lu-DOTATATE injection

The eligible subjects who participate in 177Lu study are randomly assigned 1:1 to either the test group or the control group to receive treatment. Subjects in the test group are treated with 177Lu-DOTATATE injection, 7.4GBq±0.74GBq (200mCi±20mCi)/cycle, once every 8 to 12 weeks, 4 times in total.

DRUG

Octreotide LAR (Long-acting release)

The eligible subjects who participate in 177Lu study are randomly assigned 1:1 to either the test group or the control group to receive treatment. Subjects in the treatment group are treated with 60mg of long-acting octreotide once every 4 weeks±3 days.

Trial Locations (1)

100730

RECRUITING

Peking Union Medical College Hospital, Beijing

All Listed Sponsors
lead

HTA Co., Ltd.

INDUSTRY