Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

August 1, 2025

Study Completion Date

August 1, 2026

Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
DRUG

Adebrelimab

1200mg, intravenous infusion, D1, Every three weeks, there are two cycles in total.

DRUG

TP regimen

TP regimen: Docetaxel 75 mg/m2, intravenous infusion, D1, Cisplatin 75 mg/m2, intravenous infusion, D1, Every three weeks, there are two cycles in total.

PROCEDURE

Surgery or radiotherapy

Surgery or radiotherapy should be performed 1-4 weeks after the completion of neoadjuvant therapy.

Trial Locations (1)

250117

RECRUITING

Cancer Hospital of Shandong First Medical University, Jinan

All Listed Sponsors
lead

Xiuping Ding

OTHER