34
Participants
Start Date
November 1, 2025
Primary Completion Date
July 1, 2026
Study Completion Date
November 1, 2026
Elderberry Anthocyanin Chewing Gum
Participants receive a functional chewing gum containing encapsulated elderberry (Sambucus nigra L.) anthocyanins standardized for cyanidin-3-glucoside and cyanidin-3-sambubioside. The gum is formulated to be geriatric-friendly (soft, low-elasticity) and is administered twice daily for 6 weeks. It enables transmucosal polyphenol delivery through buccal absorption.
Placebo Chewing Gum
Participants receive a placebo chewing gum identical in appearance, taste, and texture to the active gum but containing no elderberry anthocyanins or bioactive compounds. The gum is administered twice daily for 6 weeks to match the intervention group.
Mehmet Akif Ersoy University, Burdur
Burdur Mehmet Akif Ersoy University
OTHER