A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

July 2, 2025

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Dry Eye
Interventions
DRUG

Perfluorohexyloctane ophthalmic solution

Eligible subjects will receive Miebo up to 4 times bilaterally on Day 1/Visit 1 (1 drop instilled bilaterally by site staff in-clinic while wearing contact lenses and the rest self-administered throughout the remainder of the day while wearing contact lenses). Starting on Day 2, subjects will self-administer the first drop of Miebo bilaterally before inserting contact lenses for the day. Subjects will wait 30 minutes after the first dose of Miebo to insert their contact lenses and will then instill 3 additional drops of Miebo while wearing contact lenses approximately evenly spaced throughout the rest of the day. Subjects will continue to self-administer Miebo QID bilaterally following the dosing schedule from Day 2 for approximately 30 days. Subjects are expected to record daily VAS assessments throughout the study. The VAS assessments will be collected by the sites at Visits 2, 3, and 4.

Trial Locations (8)

13850

Site 108, Vestal

32779

Site 107, Longwood

37205

Site 106, Nashville

45701

Site 103, Athens

55340

Site 102, Medina

66762

Site 104, Pittsburg

92307

Site 101, San Diego

94112

Site 105, San Francisco

All Listed Sponsors
lead

Bausch & Lomb Incorporated

INDUSTRY