"HBV unIversal vs Point-Of-Care-based Antiviral treatMent to Prevent Mother-to-child Transmission"

HBsAg will be screened using finger-stick capillary blood during the ANC visit, simultaneously with the HIV test

300mg per day or 300 mg every 2 days (if créatinine clearance is 30-50ml/min)

300mg per day or 300 mg every 2 days (if créatinine clearance is 30-50ml/min)

"The social sciences component only in Cambodia and Ivory Coast. 3 key sub-studies: i) a socio-economic and behavioral study ii) a health economic evaluation study, and iii) a health policy study.~A mixed-methods approach will be used, including qualitative interviews and quantitative questionnaires among pregnant women and healthcare workers"

At 9 months, all infants will be tested for HBsAg; HBsAg-positive infants will undergo HBV DNA testing, and DBS will be collected for biobank storage.