Patient Derived Organoids (PDOs) to Observe the Clinical Consistency of Personalized Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma

RecruitingOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

February 28, 2026

Study Completion Date

July 31, 2026

Conditions
Esophageal Cancer
Interventions
DRUG

Neoadjuvant Chemotherapy (NACT)

"The planned regimen for neoadjuvant therapy may include one or more of the following agents:~1. Paclitaxel Injection~2. Albumin-bound paclitaxel Injection (Abraxane® equivalent formulation)~3. Cisplatin Injection~4. Carboplatin Injection~5. Nivolumab~6. Pembrolizumab~7. Toripalimab~8. Tirilibumab~9. Camrelizumab The specific agent(s) and their combination will be selected based on the patient's clinical treatment protocol. The final regimen must be approved jointly by the principal investigator and the attending physician according to established clinical guidelines and individualized patient factors."

Trial Locations (1)

200032

RECRUITING

Zhongshan Hospital, Fudan University, Shanghai

All Listed Sponsors
collaborator

Accurate International Biotechnology (Guangzhou) Co., Ltd.

UNKNOWN

lead

Shanghai Zhongshan Hospital

OTHER