NCT07053475View on ClinicalTrials.gov

IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches

PHASE4RecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

April 2, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

March 31, 2027

Conditions
Heart FailureHeart Failure With Reduced Ejection Fraction (HFrEF)Heart Failure With Preserved Ejection Fraction (HFPEF)Iron DeficiencyIron-deficiency Anemia (IDA)
Interventions
DRUG

Ferric Carboxymaltose

Intravenous infusion of 1 gram FCM during index hospital stay, followed by a second dose at Week 6 (1,000 mg if \> 70 kg or 500 mg if ≤ 70 kg).

DRUG

Ferrous Sulfate

Oral administration of one 150 mg capsule every 48 hours for 12 weeks.

Trial Locations (1)

42101

RECRUITING

The Medical Center, Bowling Green

Sponsors

Collaborators (1)

American Regent, Inc.
All Listed Sponsors
collaborator

American Regent, Inc.

INDUSTRY

lead

Syed Hamza Mufarrih

OTHER