3,200
Participants
Start Date
August 1, 2025
Primary Completion Date
November 15, 2029
Study Completion Date
November 15, 2029
Inhaled corticosteroid (ICS)
Participants will use either a combination of budesonide/formoterol or mometasone/formoterol as both controller and rescue therapy or a stand alone inhaled steroid (beclomethasone, budesonide, fluticasone, mometasone, ciclesodine) of their choice with their current reliever therapy or be converted to budesonide/albuterol as rescue therapy.
Azithromycin
Participants will take 500mg of azithromycin three times a week or 10mg/kg if under 50Kg which may be reduced to 250mg/Kg for side effects.
Asthma Symptom Monitoring Web-based Application
All participants will be provided access to the Asthma Symptom Monitoring (ASM) tools. ASM can be integrated with electronic health records (EHR) or used as a stand alone application. Participants will answer 5 questions about their asthma each week. If symptoms are problematic, participants can request a call back from a person on their care team. Participants can view a graph of their data, watch videos, and record peak flows. Clinicians and members of the care team can view data in the EHR (not for stand alone web app).
Mt. Sinai School of Medicine, New York
University North Carolina, Chapel Hill
Atrium Health, Charlotte
AdventHealth, Orlando
University of Missouri, Columbia
University of Kansas, Kansas City
JPS Health Network, Fort Worth
Kelsey Research Foundation, Houston
DARTNet Institute, Aurora
University Colorado-Denver, Aurora
University of Washington, Seattle
Reliant Medical Group, Worcester
Rutgers Robert Wood Johnson Medical School, New Brunswick
Lead Sponsor
Collaborators (2)
Penn State University
OTHER
Icahn School of Medicine at Mount Sinai
OTHER
University of Colorado, Denver
OTHER
RAND
OTHER
University of Washington
OTHER
University of North Carolina
OTHER
Reliant Medical Group
OTHER
Kelsey Research Foundation
OTHER
University of Kansas
OTHER
University of Missouri-Columbia
OTHER
John Peter Smith Health Network
UNKNOWN
Rutgers University
OTHER
AdventHealth
OTHER
Wake Forest University Health Sciences
OTHER
DARTNet Institute
OTHER_GOV