The Effects of Exogenous Ketones on Cognitive Function

NARecruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

October 8, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Placebo - ControlKetone Monoester
Interventions
DIETARY_SUPPLEMENT

Ketone Monoester (KE)

Participants will undergo two test days separated by 3-7 days. On both test days, participants will arrive fasted and consume a single dose of ketone monoester or placebo (357 mg/kg of body weight) in random order. Drinks will be prepared by non-study personnel and matched in taste, texture, and appearance to maintain blinding. Thirty minutes after consuming the ketone monoester or placebo, cognitive assessments will be completed including NIH Toolbox cognitive assessments, Senaptec Sensory Station, and driving simulation.

DIETARY_SUPPLEMENT

Placebo

Participants will undergo two test days separated by 3-7 days. On one test day, participants will consume a single dose of placebo (357 mg/kg of body weight). Thirty minutes after consuming the placebo, cognitive assessments will be completed including NIH Toolbox cognitive assessments, Senaptec Sensory Station, and driving simulation.

Trial Locations (1)

35205

RECRUITING

916 Building, Birmingham

All Listed Sponsors
lead

University of Alabama at Birmingham

OTHER

NCT07051655 - The Effects of Exogenous Ketones on Cognitive Function | Biotech Hunter | Biotech Hunter