Efficacy and Safety of Rituximab in the Treatment of Anti-Vimentin Antibody-associated Diseases

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

October 1, 2026

Study Completion Date

November 1, 2026

Conditions
Anti-Vimentin Antibody-associated DiseasesMeningoencephalomyelitis Associated With Vimentin IgG Autoantibodies
Interventions
DRUG

RTX treatment

This study used a drug dosage based on previous domestic and international literature as well as clinical experience from our center, set at 375mg/m2 per dose. During the course of the disease, TB lymphocyte subsets are monitored, and if the proportion of B lymphocytes is greater than or equal to 1%, a second dose will be administered.

Trial Locations (1)

Unknown

Xuanwu Hospital, Capital Medical University, Beijing

All Listed Sponsors
lead

Xuanwu Hospital, Beijing

OTHER