QL1706 Plus Celecoxib in Advanced Esophageal Squamous Cell Carcinoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

July 15, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

September 1, 2027

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
DRUG

QL1706 Plus Celecoxib Group

QL1706 (anti-PD-1/CTLA-4 bispecific antibody) will be administered at 5 mg/kg by intravenous infusion every 3 weeks. Celecoxib 200 mg will be taken orally twice daily starting on Day 1 of each 3-week treatment cycle. Treatment continues until disease progression, intolerable toxicity, or for a maximum of 2 years.

All Listed Sponsors
lead

Peking University Cancer Hospital & Institute

OTHER