ICOPE INTENSE-K Pilot Study

The ICOPE-intense intervention (45 hours centre-based (in-group and in-person) multidomain intervention, everyday home-based lifestyle improvement, and weekly individual phone/video call for support)

12.5g once a day of KE for week 1, and 25g once a day of KE supplementation week 2 to week 8.

2.5 g of nonketogenic canola oil

2 sprays (i.e. 2000 iu) per day in the morning for 60 days

1000 mg: 1 table per day in the morning during 60 days

5 mg cp: 1 tablet morning and 1 tablet evening for 60 days

250 microgram: 1 tablet per day in the morning for 30 days, then 1 tablet every 10 days for 30 days

In case of Sarcopenia or low protein intake (\<1.2 g/kg/day), Oral Nutritional Supplementation enriched in essential amino acid (leucin)

usual ICOPE Step 1