Single Arm Romiplostim to Prevent CIT

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

January 26, 2024

Primary Completion Date

January 1, 2027

Study Completion Date

January 1, 2028

Conditions
Ewings SarcomaChemotherapy Induced Thrombocytopenia
Interventions
DRUG

Romiplostim (AMG-531)

Romiplostim may be started as supportive care, as early as cycle 1 day 1; all patients MUST initiate romiplostim no later than 2 weeks from the start of the 5th cycle of chemotherapy (see exception below for patients with platelet count of 200,000 or greater). If plt count \< 200,000/mm3, patients will start romiplostim based on their weight

Trial Locations (1)

45229

RECRUITING

Cincinnati Children's Hospital Medical Center, Cincinnati

All Listed Sponsors
lead

Children's Hospital Medical Center, Cincinnati

OTHER