Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

386

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

October 31, 2029

Study Completion Date

October 31, 2030

Conditions
Chronic Obstructive Pulmonary Disease ExacerbationObstructive Sleep Apnea Exacerbation
Interventions
DEVICE

Non-invasive Ventilation (NIV)

Patients will receive a dedicated training for the use of their NIV in the home setting. The training is the same provided in the usual care of patients established on NIV. They will choose a home care provider for the delivery of NIV as per standard care in France. A telemonitoring of adherence to NIV will be performed.

DEVICE

Continous Positive Airway Pressure (CPAP)

Patients will receive a dedicated training the use of their CPAP in the home setting. The training is the same provided in the usual care of patients established on CPAP. They will choose a home care provider for the delivery of CPAP as per standard care in France. Follow-up of CPAP will be performed according to standard care in France and will therefore include a telemonitoring of adherence to CPAP.

Trial Locations (1)

75013

Hospital Pitié-Salpêtrière - Sleep unit, R3S Departement, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER