Developing Hyperpolarized Gas MRI Signatures to Detect and Manage Acute Cellular Rejection

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 1, 2019

Primary Completion Date

March 30, 2029

Study Completion Date

March 31, 2029

Conditions
Lung Transplant Rejection
Interventions
DIAGNOSTIC_TEST

Sub study (Active): Two Lung MRI study with two navigational Bronchoscopy

Hyperpolarized Xenon-129 MRI twice with navigational bronchoscopy twice

DRUG

Hyperpolarized Xenon129

Lung transplant recipient with hyperpolarized Xe129 in MRI as an inhalation contrast agent

Trial Locations (1)

22908

RECRUITING

University of Virginia, Charlottesville

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Virginia

OTHER