Remimazolam and Emergence Delirium in Pediatrics

PHASE4RecruitingINTERVENTIONAL
Enrollment

248

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

January 1, 2027

Study Completion Date

January 1, 2027

Conditions
PediatricNeurosurgerySevoflurane AnesthesiaRemimazolamEmergence Delirium
Interventions
DRUG

Remimazolam

After anesthesia induction, a loading investigational drug at a rate of \[3.6\*kg\] ml/h (lasting for 5 minutes, equivalent to 0.3 mg/kg of remimazolam), and then adjust the infusion rate to \[1\*kg\] ml/h (equivalent to 1 mg/kg of remimazolam). The infusion is expected to stop 10 minutes before the end of the surgery.

DRUG

Normal Saline

After anesthesia induction, a loading investigational drug at a rate of \[3.6\*kg\] ml/h (lasting for 5 minutes, equivalent to 0.3 mg/kg of normal saline), and then adjust the infusion rate to \[1\*kg\] ml/h (equivalent to 1 mg/kg of normal saline). The infusion is expected to stop 10 minutes before the end of the surgery.

Trial Locations (2)

100034

NOT_YET_RECRUITING

Peking University First Hospital, Beijing

RECRUITING

Peking University First Hospital, Beijing

All Listed Sponsors
lead

Peking University First Hospital

OTHER

NCT07046364 - Remimazolam and Emergence Delirium in Pediatrics | Biotech Hunter | Biotech Hunter