A Clinical Trial Evaluating Injection of TQB6411 in Subjects With Advanced Malignant Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

216

Participants

Timeline

Start Date

July 15, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2028

Conditions
Advanced Malignant Tumors
Interventions
DRUG

TQB6411 injection

TQB6411 for injection is an antibody-conjugated drug (ADC) targeting EGFR/c-Met. After injecting intravenously, the antibody part of this product binds to the EGFR and c-Met on the surface of tumor cells to block the activation of EGFR and c-Met signaling pathways. The ADC is enrolled and transported to the lysosome through cells. The linker releases toxins after enzyme cleavage, resulting in DNA damage and cell death.

Trial Locations (3)

200000

NOT_YET_RECRUITING

Shanghai Jiaotong University School of Medicine, Renji Hospital, Shanghai

NOT_YET_RECRUITING

Shanghai Pulmonary Hospital, Shanghai

450052

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

All Listed Sponsors
lead

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

INDUSTRY

NCT07043751 - A Clinical Trial Evaluating Injection of TQB6411 in Subjects With Advanced Malignant Tumors | Biotech Hunter | Biotech Hunter