WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-Making

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2029

Conditions
Hyperparathyroidism, PrimaryParathyroid NeoplasmsParathyroid AdenomaHypocalcemia
Interventions
DEVICE

Near-Infrared Parathyroid Tissue Sensor Imaging (PTS)

FDA-cleared imager (e.g., Fluobeam LX/PTeye) providing real-time autofluorescence to identify parathyroid tissue during surgery; no dye or radiation.

PROCEDURE

Rim-Preservation Technique

Surgical excision of adenoma while leaving the NIRAF-positive rim of normal parathyroid tissue in situ; minimal defatting to ensure perfusion.

PROCEDURE

En-bloc Resection Technique

Surgical excision of adenoma together with the surrounding NIRAF-positive rim; autotransplant fragment if \< 2 normal glands remain in neck.

Trial Locations (1)

350001

Fujian Medical University Union Hospital, Fuzhou

All Listed Sponsors
lead

Fujian Medical University

OTHER