Efficacy of Peripheral Nerve Blocks in Total Knee Arthroplasty

NARecruitingINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

June 8, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

June 1, 2026

Conditions
Postoperative Pain Following Knee Arthroplasty
Interventions
OTHER

Opioid Analgesic (tramadol hydrochloride)

For postoperative pain management, a patient-controlled analgesia (PCA) pump will be routinely applied to the patient in our clinic. An infusion of an opioid (tramadol hydrochloride) at an appropriate dose will be administered via intravenous route through the pump, and the patient will be provided with detailed information about its use. Instead of continuous infusion, the device will deliver intermittent bolus doses when the patient's numeric rating scale (NRS) score is 4 or higher.

OTHER

Prophylactic analgesia (intravenous paracetamol)

All patients will receive routine prophylactic analgesia with 1 gram of intravenous paracetamol every 6 hours (which may be skipped if the patient's pain score is 2 or below and they do not request pain relief).

OTHER

Rescue analgesia (intramuscular diclofenac sodium)

If the pain persists despite the administered analgesics and the patient's pain score remains 4 or above, rescue analgesia with intramuscular diclofenac sodium, which is routinely used in our clinic, will be administered.

Trial Locations (1)

60100

RECRUITING

Tokat Gaziosmanpasa University, Tokat Province

All Listed Sponsors
lead

Tokat Gaziosmanpasa University

OTHER

NCT07040709 - Efficacy of Peripheral Nerve Blocks in Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter