Negative Pressure Wound Therapy for Split Thickness Skin Grafting to the Lower Leg After Excision of Skin Tumour: A Multicentre Randomised Study

NANot yet recruitingINTERVENTIONAL
Enrollment

242

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

March 31, 2028

Conditions
Skin TransplantationSkin GraftingSplit Thickness Skin GraftNegative-Pressure Wound TherapyPostoperative ComplicationsSurgical Wound InfectionLower ExtremitySkin CancerSkin TumourWound HealingBandagesLeg
Interventions
DEVICE

Negative Pressure Wound Therapy (NPWT)

Negative pressure wound therapy (NPWT) applied over the split-thickness skin graft on the lower leg after tumour excision. A protective silicone interface layer will be used, with continuous negative pressure of -125 mmHg applied until postoperative day 5, unless earlier change is clinically indicated.

OTHER

Traditional Dressing

Traditional dressing applied over the split-thickness skin graft on the lower leg after tumour excision. The dressing consists of one or more layers of foam dressing applied on top, which may or may not be fixed with sutures according to surgeon preference, and an elastic bandage applied over the foam to provide gentle, even compression and immobilisation of the graft. The dressing will remain undisturbed until postoperative day 5 unless earlier change is clinically indicated.

Trial Locations (1)

20501

Dept. of Plastic and Reconstructive Surgery and Dept. of Health Sciences, Skåne University Hospital, Malmö, Sweden., Malmo

All Listed Sponsors
lead

Region Skane

OTHER