NCT07040566View on ClinicalTrials.gov

A Trial of Varenicline for E-cigarette Cessation

PHASE2RecruitingINTERVENTIONAL
Enrollment

326

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

January 31, 2029

Study Completion Date

January 31, 2029

Conditions
E-cigarette UseVapingNicotine Dependence
Interventions
DRUG

Varenicline 1mg BID

12 weeks following the standard titration of 1 mg, twice daily

DRUG

Placebo

Matching placebo twice daily

Trial Locations (2)

29425

NOT_YET_RECRUITING

Hollings Cancer Center at MUSC (HCC), Charleston

06520

RECRUITING

Yale Cancer Center/Smilow Cancer Hospital at Yale-New Haven, New Haven

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Yale University

OTHER