Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2028

Conditions
HNSCC
Interventions
COMBINATION_PRODUCT

Stapokibart and Finotonlimab

"Receive the combination of Stapokibart and Finotonlimab in cycles 1-3, and maintain treatment with Finotonlimab in subsequent cycles.~Stapokibart, 600mg for the first cycle, 300mg for the second and third cycles, administered subcutaneously every 3 weeks, for a total of 3 doses of Stapokibart; Finotonlimab 200mg, administered intravenously every 3 weeks until confirmed disease progression occurs according to the RECIST 1.1 imaging criteria (if the researcher determines that the subject can benefit from continuing PD-1 drug treatment, and the subject can tolerate the study treatment and agree, PD-1 drug can be continued and recorded in the study records), unacceptable toxic side effects, initiation of new anti-tumor treatment, withdrawal from the study or death (whichever occurs first), or reaching a maximum treatment period of 2 years."

Trial Locations (1)

Unknown

Beijing Tongren Hospital, Capital Medical University, Beijing

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Keymed Biosciences Co.Ltd

INDUSTRY

collaborator

Sinocelltech Ltd.

INDUSTRY

lead

Beijing Tongren Hospital

OTHER

NCT07040072 - Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC | Biotech Hunter | Biotech Hunter