Toripalimab Combined With Chemotherapy as Adjuvant Therapy for Non-small Cell Lung Cancer With or Without Prior Neoadjuvant Therapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

211

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

December 30, 2028

Study Completion Date

December 31, 2030

Conditions
Stage IB-IIIB NSCLCStage IIB-III NSCLC
Interventions
DRUG

Toripalimab

Participants will receive Toripalimab (240 mg IV) Q3W for 17 cycles (cycle length=21 days).

DRUG

Cisplatin-based chemotherapy

Cisplatin\[75 mg/m\^2 IV Q3W\]/carboplatin\[AUC 5 IV Q3W\]+paclitaxel\[260 mg/m\^2 IV Q3W\] or cisplatin\[75 mg/m\^2 IV Q3W)\]/carboplatin\[AUC 5 IV Q3W\]+ pemetrexed\[500 mg/m2 IV Q3W\],dependent on tumor histology. Participants will receive Chemotherapy for 3-4 cycles

Trial Locations (1)

510080

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

All Listed Sponsors
collaborator

Shanghai Junshi Bioscience Co., Ltd.

OTHER

lead

Wen-zhao ZHONG

OTHER