NCT07037771View on ClinicalTrials.gov

A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

PHASE3RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 17, 2025

Primary Completion Date

August 20, 2027

Study Completion Date

August 20, 2027

Conditions
Homozygous Familial Hypercholesterolemia
Interventions
DRUG

zodasiran Injection

ARO-ANG3 Injection

DRUG

Placebo

sterile normal saline (0.9% NaCl)

Trial Locations (2)

10029

RECRUITING

Research Site 2, New York

45227

RECRUITING

Research Site 1, Cincinnati

Sponsors
All Listed Sponsors
lead

Arrowhead Pharmaceuticals

INDUSTRY