Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

July 31, 2028

Study Completion Date

January 31, 2029

Conditions
Knee Osteoarthritis (Knee OA)Knee Osteoarthritis (OA)
Interventions
DRUG

Somatropin (recombinant human growth hormone)

Study participants will deliver Somatropin via self-administered subcutaneous injection into the abdomen or gluteal region once per day for six weeks at a dose of 0.5mg/day per body surface area (0.5mg/m2/day).

DRUG

bacteriostatic saline placebo

Study participants will deliver bacteriostatic saline via self-administered subcutaneous injection into the abdomen or gluteal region once per day for six weeks in an identical delivery device to the experimental arm.

Trial Locations (1)

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

All Listed Sponsors
collaborator

Sunnybrook Research Institute

OTHER

lead

Dr. David Wasserstein

OTHER

NCT07036003 - Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR) | Biotech Hunter | Biotech Hunter