Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer

Not yet recruitingOBSERVATIONAL
Enrollment

34

Participants

Timeline

Start Date

June 16, 2025

Primary Completion Date

June 15, 2027

Study Completion Date

June 15, 2028

Conditions
Carbon Ion Radiotheray
Interventions
RADIATION

Carbon ion radiotherapy

Patients will receive platinum-based doublet chemotherapy and immunotherapy, followed by carbon iron radiotherapy and immunotherapy. The concrete immune checkpoint inhibitor includes durvalumab, sugemalimab, atezolizumab, benmelstobart, pembrolizumab, camrelizumab, toripalimab, tislelizumab, sintilimab, nivolumab, serplulimab, or penpulimab.

DRUG

Chemotherapy

platinum-based doublet chemotherapy

DRUG

Immunotherapy

The concrete immune checkpoint inhibitor includes durvalumab, sugemalimab, atezolizumab, benmelstobart, pembrolizumab, camrelizumab, toripalimab, tislelizumab, sintilimab, nivolumab, serplulimab, or penpulimab.

Trial Locations (1)

310022

Zhejiang Cancer Hospital, Hangzhou

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Ji Yongling

OTHER

NCT07035860 - Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer | Biotech Hunter | Biotech Hunter