Effect of Sevoflurane on Sweat Threshold in Children of Different Ages

NANot yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

June 30, 2026

Conditions
Child, OnlyTemperature Regulation; DisorderLow Body TemperaturesSevoflurane
Interventions
DEVICE

temperature monitoring

Core temperature will be measured in the distal esophagus. The esophageal probe will be inserted after intubation to the depth from the upper incisors recommended by Bloch et al,1 specifically one-quarter of the patient's height plus 4.5 cm.

DRUG

Sevoflurane

Anesthesia induction will be standardized for all participants., the children will undergo inhalational induction using 8% sevoflurane with a fresh gas flow of 5 L/min in 100% oxygen. Once children loses consciousness, the sevoflurane concentration will be reduced to 3%-5% and then maintained as close as possible to 1.2 MAC, age-adjusted

Trial Locations (1)

Unknown

The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou, Wenzhou

All Listed Sponsors
lead

Second Affiliated Hospital of Wenzhou Medical University

OTHER