Phase II Clinical Study on the Safety and Efficacy of Combined CAR-T Therapy Following Autologous Stem Cell Transplantation in Multiple Myeloma

NANot yet recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

March 1, 2028

Study Completion Date

April 1, 2028

Conditions
Multiple Myeloma (MM)Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)Chimeric Antigen Receptor T-cell
Interventions
OTHER

autologous hematopoietic stem cell transplantation (ASCT) followed by CAR-T therapy

The efficacy of autologous hematopoietic stem cell transplantation (ASCT) followed by CAR-T therapy was evaluated in patients with multiple myeloma who either achieved partial response (PR) or better (but not complete response \[CR\]) after four cycles of first-line chemotherapy, or those who achieved CR but had high-risk factors.

Trial Locations (1)

221002

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

All Listed Sponsors
collaborator

Shuyang People's Hospital

UNKNOWN

lead

The Affiliated Hospital of Xuzhou Medical University

OTHER