Probiotics and Active Aging: Enhancing Gut Health

NANot yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

January 31, 2026

Study Completion Date

June 30, 2026

Conditions
Gut -MicrobiotaOlder PeoplePhysical ActivityPhysical FitnessMental HealthProbioticHealthy
Interventions
OTHER

Dietary Supplement

A daily oral capsule containing 1 x 10⁹ CFU of Lactiplantibacillus plantarum CECT 7481 (32.5 mg), microcrystalline cellulose (304.1 mg), and magnesium stearate (3.4 mg). Administered once daily before the main meal for 6 weeks. Used to evaluate its effects on gut microbiota and physical health in older adults.

OTHER

Placebo

A daily oral capsule identical in appearance to the probiotic capsule, containing maltodextrin instead of Lactiplantibacillus plantarum. Administered once daily before the main meal for 6 weeks. Used to control for placebo effects in the assessment of probiotic efficacy.

BEHAVIORAL

Structured Physical Activity Program

A 12-week supervised physical activity program conducted at municipal sports centers. Participants engage in moderate-intensity exercise at least 2 times per week. Designed to assess the impact of physical activity on gut microbiota, physical condition, and quality of life in older adults.

All Listed Sponsors
lead

Jose Luis Felipe

OTHER

NCT07033637 - Probiotics and Active Aging: Enhancing Gut Health | Biotech Hunter | Biotech Hunter