Prevalence of Human Papillomavirus (HPV) in a Healthy Population: A Feasibility Study of Oropharyngeal Cancer Screening

NARecruitingINTERVENTIONAL
Enrollment

20,000

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

December 31, 2030

Study Completion Date

March 30, 2031

Conditions
Oropharynx Cancer
Interventions
DIAGNOSTIC_TEST

Self-sampling by gargling kit at dental clinic

Participants will perform a self-sampling at the dental clinic using gargling kit

OTHER

Questionnaire

Participants will answer questionnaire online/paper at their home or at the dental clinic

DIAGNOSTIC_TEST

Self-sampling by gargling kit at home

Participants will perform a self-sampling at home using gargling kit

DIAGNOSTIC_TEST

Blood sampling

Venous blood will be collected from study participants with oral hrHPV positivity, in which the presence of circulating hrHPV DNA will be determined.

DIAGNOSTIC_TEST

Self-sampling of the urogenital area

In case of a positive examination in the oropharynx, the tested individuals will be offered a self-collection HPV examination in the urogenital area (cervicovaginal swab in women or external genital swab in men).

Trial Locations (1)

77900

RECRUITING

Klinika zubního lékařství Fakultní nemocnice Olomouc, Olomouc

All Listed Sponsors
collaborator

National Institute for Cancer Research, Czech Republic

OTHER

lead

The Institute of Molecular and Translational Medicine, Czech Republic

OTHER

NCT07033091 - Prevalence of Human Papillomavirus (HPV) in a Healthy Population: A Feasibility Study of Oropharyngeal Cancer Screening | Biotech Hunter | Biotech Hunter