IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

June 2, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2028

Conditions
Gastric Cancer
Interventions
DRUG

IBI343

"Subjects in the phase 1b stage will receive IBI343 3/4.5/6mg/kg intravenous infusion (IV) D1 Q3W in 3-week cycles.~Subjects in the phase 2 stage will receive IBI343 RP2D intravenous IV D1 Q3W in 3-week cycles."

DRUG

Sintilimab

Subjects will receive sintilimab 200mg IV D1 Q3W in 3-week cycles.

DRUG

Oxaliplatin

Subjects will receive oxaliplatin 130mg/m2 IV D1 Q3W in 3-week cycles.

DRUG

S-1

Subjects will receive S-1 40-60mg BID PO D1-14 Q3W in 3-week cycles.

Trial Locations (1)

200025

RECRUITING

Shanghai Jiao Tong University School of Medicine, Shanghai

All Listed Sponsors
collaborator

Shanghai Jiao Tong University School of Medicine

OTHER

lead

Ruijin Hospital

OTHER

NCT07025889 - IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer | Biotech Hunter | Biotech Hunter